The Arrigo Recordati Prize

Milan, May 18th 2023

The International Prize for Scientific Research Arrigo Recordati

Young Investigator Award for Excellence in neuroblastoma research

CALL FOR APPLICATIONS

The International Prize for Scientific Research Arrigo Recordati was established in 2000 in memory of the Italian pharmaceutical entrepreneur Arrigo Recordati to perpetuate his legacy and to inspire biomedical discoveries benefiting people worldwide. Arrigo Recordati, who passed away prematurely in 1999, strongly believed in the power of research to drive the development of the pharmaceutical industry and provide products beneficial to public health and individual well-being.

Over the last fifteen years, Recordati has developed, produced and marketed medicines for the treatment of rare diseases through Recordati Rare Diseases, dedicated entirely to serving patients globally living with rare conditions and focused on key treatment areas including rare metabolic, endocrine and oncology.

To reflect its commitment in pediatric oncology, Recordati decided that the 11th edition of the International Prize for Scientific Research Arrigo Recordati will be dedicated to the promotion and recognition of excellence in research on pediatric oncology, specifically neuroblastoma.

Young investigators of all nationalities working in this area are eligible. Applicants should be independent junior faculty who are not more than ten years from their terminal degree or eight years from the end of their fellowship and who are not employed full-time with a pharmaceutical company.

Basic, translational, preclinical, and clinical research projects focusing on neuroblastoma are eligible.

The winning project will receive a € 100,000 research grant.

No institutional indirect costs (e.g., overhead costs) will be added or subtracted to\from the grant. However, if there is a requirement for an indirect cost payable to the institution, a special request must be made to Recordati S.p.A. explaining the special circumstances.

If approved, the maximum indirect rate would be 10% of the Prize.

An annual progress report of the research project is expected.

2024 Review Committee

Applications will be reviewed by an independent panel of internationally recognised experts who have provided leadership throughout their long careers in the field of rare diseases.

For the 2024 Award, the Review Committee is composed of:

Chairman:
Prof. Robert J. Desnick,
M.D., PhD., D.SC. (Hon),
Dean for Genetics and Genomic Medicine, Professor and Chairman Emeritus Department of Genetics & Genomic Sciences,
The Icahn School of Medicine at Mount Sinai, New York City, NY, USA

Prof. Andrew Pearson,
M.D., PhD.,
Retired Cancer Research
Professor of Paediatric Oncology, Institute of Cancer Research and the Royal
Marsden Hospital NHS Trust,
Sutton, UK

Prof. Charles Patrick Reynolds,
M.D., PhD.,
Cancer Center Director, Professor of Pediatrics,
Cell Biology & Biochemistry,
and internal medicine,
School of Medicine, Texas
Tech University Health Sciences Center, Lubbock, USA

Recordati recognises the value of basic research to elucidate the pathophysiology and the etiology of pediatric neuroblastoma, translational research to develop new diagnostic and therapies for early intervention, and clinical research to develop novel therapeutic strategies. Such research projects are sought for this competition.

Proposals should be based on strong preliminary results which support the project rationale.

If a proposed experimental treatment is based on a pre-existing treatment, the project is eligible only if the treatment is being repurposed from another indication or if its formulation, or administration is changed in a major way, in order to improve treatment quality, compliance, efficacy, safety, or any other significant patient benefit.

Intellectual Property Rights, when relevant, will be safeguarded.

Previous research activity and publications will be a major component for the assessment of proposals.

2024 Award Ceremony

The winning project will be formally announced during an Award Ceremony at SIOP Europe Congress (International Society of Pediatric Oncology Europe) which will be held in Italy from 13th to 17th May 2024.

2024 Application Procedure

The Application will follow a two-step selection process:

1) Preselection: from June 1st 2023 to September 30th 2023

Initial proposals in English must be submitted online in the preselection period described above and should include:

  • a Letter of Intent (see below)
  • the Project Summary Page (see below) describing the proposed project in 1200 words (plus one page for figures and/or tables).

The Application Form for the initial proposals must be submitted online at: www.prize.recordati.it

Applicants who submit an initial proposal will receive an email confirming receipt.

The Review Committee, and ad hoc experts, if needed, will evaluate all initial proposals to determine which Applicants will be invited to submit Full Research Project Applications.

Projects eligible for Full Research Project Application will be communicated to the Applicant by November 15th, 2023.

Eligibility criteria

Applicants should be independent junior faculty who are not more than ten years from their terminal degree or eight years from the end of their fellowship and who are not employed full-time with a pharmaceutical company.

  • The Applicant must be the Principal Investigator of the research project and her/his role in the project must be clearly delineated.
  • The Applicant’s CV should be included.
  • Applicants should use the Application Form and comply with instructions.

Exclusion criteria

  • Projects sponsored by other pharmaceutical companies
  • Projects already completed.

2) Full Applications: from November 16th, 2023 to February 28th, 2024

Applicants of the selected initials proposals will be invited to submit a Full Research Project Application for competitive review.

Full Research Project Applications instructions must be downloaded from www.prize.recordati.it

The Review Committee will assess and select the winning project based on the quality of the proposed research.

The Review Committee will follow the “code of conduct” guidance to ensure that reviews are conducted in a fair and equitable manner. The members of the Review Committee are bound by the confidentiality rules generally applicable to such committees.

Applications from the Review Committee members or from faculty of their respective institutions will not be considered.

The Review Committee’s decision is final and there is no appeal mechanism.

2024 Preselection: initials proposal instructions

Application Form

The Application Form must include a Letter of Intent and the Project Summary Page. The steps to apply are the following:

  1. Preselection of the initial proposals is based on the Letter of Intent and the Project Summary Page.
  2. Applicants of the selected initial proposals will be invited to submit Full Research Project Applications to compete for the Award by November 15th, 2023.

The selection of the winning project will be based on the evaluation of the Review Committee, and if necessary, ad hoc experts, who will assess the quality of the research as well as the potential impact of the results.

Letter of Intent

The Letter of Intent is an endorsement of the Principal Investigator and the proposed project by an administrative official of the Applicant’s medical school, hospital, or research institute.

Project Summary Page

In 1200 words (plus one page for figures and/or tables) not including reference (Font: Times New Roman 12 or Arial 11, all margins 0.5 inches / 12.7 mm), succinctly describe the proposed project including:

  1. background, unmet needs, and significance of the project;
  2. specific aims, objectives, or hypothesis;
  3. preliminary studies and data relevant to the proposed project;
  4. experimental design: description of methods and analyses to be performed for basic and translational research projects. If a clinical trial is proposed, present the trial design, with primary & secondary endpoints, as well as a statistical plan.
  5. expected results and expected timeframe for completing the project.

Applicants should feel free to add any additional information/supportive data, as needed within the 1200 words limit.

 

To submit an application: 
www.prize.recordati.it

Contacts: recordatiprize2024@recordati.com